Delivering new horizons for heart health

Esperion is a pharmaceutical company focused on developing and commercializing first-in-class, oral,
low-density lipoprotein cholesterol (LDL-C) lowering therapies for the treatment of patients with
elevated LDL-C.

Many patients with elevated LDL-C have LDL-C levels not adequately controlled with current lipid-modifying therapies. Patients with elevated LDL-C only able to tolerate less than the lowest approved daily starting dose of a statin can be considered having “statin intolerance“. Our lead product candidate, bempedoic acid (ETC-1002), is a first-in-class, orally available, small molecule designed to significantly lower elevated levels of LDL-C — with reduced potential for muscle-related side effects associated with statin use.

Clinical Studies

Esperion launched its global pivotal Phase 3 program, Cholesterol Lowering via BEmpedoic Acid, an ACL-inhibiting Regimen (CLEAR), with the initiation of CLEAR Harmony (1002-040). a long-term safety and tolerability study of bempedoic acid in patients with hyperlipidemia. Learn more about our planned clinical studies and results.

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Meet Esperion

Our founder and chief scientific officer, Roger Newton, co-discovered the statin marketed as Lipitor® (atorvastatin) — the most commonly prescribed LDL-C lowering therapy in the world and best-selling drug in the pharmaceutical industry’s history. Learn more about our management team’s track record of success.

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Statin Intolerance

It is estimated that approximately 10% of patients prescribed statins, 8 million patients in the U.S., Europe and Japan, are considered “statin intolerant”.

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Statin-Intolerance-Roundtable-Report