Delivering new horizons for heart health
Esperion is a pharmaceutical company focused on developing and commercializing first-in-class, oral,
low-density lipoprotein cholesterol (LDL-C) lowering therapies for the treatment of patients with
Many patients with elevated LDL-C have LDL-C levels not adequately controlled with current lipid-modifying therapies. Patients with elevated LDL-C only able to tolerate less than the lowest approved daily starting dose of a statin can be considered having “statin intolerance“. Our lead product candidate, bempedoic acid (ETC-1002), is a first-in-class, orally available, small molecule designed to significantly lower elevated levels of LDL-C — with reduced potential for muscle-related side effects associated with statin use.
Esperion launched its global pivotal Phase 3 program, Cholesterol Lowering via BEmpedoic Acid, an ACL-inhibiting Regimen (CLEAR), with the initiation of CLEAR Harmony (1002-040). a long-term safety and tolerability study of bempedoic acid in patients with hyperlipidemia. Learn more about our planned clinical studies and results.
Our founder and chief scientific officer, Roger Newton, co-discovered the statin marketed as Lipitor® (atorvastatin) — the most commonly prescribed LDL-C lowering therapy in the world and best-selling drug in the pharmaceutical industry’s history. Learn more about our management team’s track record of success.