0000001 - Document - Cover Page link:presentationLink link:calculationLink link:definitionLink 0000002 - Document - Audit Information link:presentationLink link:calculationLink link:definitionLink 0000003 - Statement - Balance Sheets link:presentationLink link:calculationLink link:definitionLink 0000004 - Statement - Balance Sheets (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 0000005 - Statement - Statements of Operations and Comprehensive Loss link:presentationLink link:calculationLink link:definitionLink 0000006 - Statement - Statements of Stockholders' Equity (Deficit) link:presentationLink link:calculationLink link:definitionLink 0000007 - Statement - Statements of Cash Flows link:presentationLink link:calculationLink link:definitionLink 0000008 - Disclosure - The Company and Basis of Presentation link:presentationLink link:calculationLink link:definitionLink 0000009 - Disclosure - Summary of Significant Accounting Policies link:presentationLink link:calculationLink link:definitionLink 0000010 - Disclosure - Collaborations with Third Parties link:presentationLink link:calculationLink link:definitionLink 0000011 - Disclosure - Inventories, net link:presentationLink link:calculationLink link:definitionLink 0000012 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 0000013 - Disclosure - Property and Equipment, net link:presentationLink link:calculationLink link:definitionLink 0000014 - Disclosure - Other Accrued Liabilities link:presentationLink link:calculationLink link:definitionLink 0000015 - Disclosure - Investments link:presentationLink link:calculationLink link:definitionLink 0000016 - Disclosure - Fair Value Measurements link:presentationLink link:calculationLink link:definitionLink 0000017 - Disclosure - Liability Related to the Revenue Interest Purchase Agreement link:presentationLink link:calculationLink link:definitionLink 0000018 - Disclosure - Convertible Notes link:presentationLink link:calculationLink link:definitionLink 0000019 - Disclosure - Stockholders' Deficit link:presentationLink link:calculationLink link:definitionLink 0000020 - Disclosure - Stock Compensation link:presentationLink link:calculationLink link:definitionLink 0000021 - Disclosure - Employee Benefit Plan link:presentationLink link:calculationLink link:definitionLink 0000022 - Disclosure - Leases link:presentationLink link:calculationLink link:definitionLink 0000023 - Disclosure - Income Taxes link:presentationLink link:calculationLink link:definitionLink 0000024 - Disclosure - Net Loss Per Common Share link:presentationLink link:calculationLink link:definitionLink 0000025 - Disclosure - Statements of Cash Flows link:presentationLink link:calculationLink link:definitionLink 0000026 - Disclosure - Summary of Significant Accounting Policies (Policies) link:presentationLink link:calculationLink link:definitionLink 0000027 - Disclosure - Inventories, net (Tables) link:presentationLink link:calculationLink link:definitionLink 0000028 - Disclosure - Property and Equipment, net (Tables) link:presentationLink link:calculationLink link:definitionLink 0000029 - Disclosure - Other Accrued Liabilities (Tables) link:presentationLink link:calculationLink link:definitionLink 0000030 - Disclosure - Investments (Tables) link:presentationLink link:calculationLink link:definitionLink 0000031 - Disclosure - Fair Value Measurements (Tables) link:presentationLink link:calculationLink link:definitionLink 0000032 - Disclosure - Liability Related to the Revenue Interest Purchase Agreement (Tables) link:presentationLink link:calculationLink link:definitionLink 0000033 - Disclosure - Stock Compensation (Tables) link:presentationLink link:calculationLink link:definitionLink 0000034 - Disclosure - Leases (Tables) link:presentationLink link:calculationLink link:definitionLink 0000035 - Disclosure - Income Taxes (Tables) link:presentationLink link:calculationLink link:definitionLink 0000036 - Disclosure - Net Loss Per Common Share (Tables) link:presentationLink link:calculationLink link:definitionLink 0000037 - Disclosure - Statements of Cash Flows (Tables) link:presentationLink link:calculationLink link:definitionLink 0000038 - Disclosure - The Company and Basis of Presentation (Details) link:presentationLink link:calculationLink link:definitionLink 0000039 - Disclosure - Summary of Significant Accounting Policies (Details) link:presentationLink link:calculationLink link:definitionLink 0000040 - Disclosure - Collaborations with Third Parties (Details) link:presentationLink link:calculationLink link:definitionLink 0000041 - Disclosure - Inventories, net (Details) link:presentationLink link:calculationLink link:definitionLink 0000042 - Disclosure - Commitments and Contingencies (Details) link:presentationLink link:calculationLink link:definitionLink 0000043 - Disclosure - Property and Equipment, net (Details) link:presentationLink link:calculationLink link:definitionLink 0000044 - Disclosure - Other Accrued Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 0000045 - Disclosure - Investments - Summary of Cash Equivalents and Short-Term Investments (Details) link:presentationLink link:calculationLink link:definitionLink 0000046 - Disclosure - Investments - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 0000047 - Disclosure - Fair Value Measurements (Details) link:presentationLink link:calculationLink link:definitionLink 0000048 - Disclosure - Liability Related to the Revenue Interest Purchase Agreement - Summary (Details) link:presentationLink link:calculationLink link:definitionLink 0000049 - Disclosure - Liability Related to the Revenue Interest Purchase Agreement - Summary of Interest Liability (Details) link:presentationLink link:calculationLink link:definitionLink 0000050 - Disclosure - Convertible Notes (Details) link:presentationLink link:calculationLink link:definitionLink 0000051 - Disclosure - Stockholders' Deficit (Details) link:presentationLink link:calculationLink link:definitionLink 0000052 - Disclosure - Stock Compensation - Stock Option and Incentive Plan (Details) link:presentationLink link:calculationLink link:definitionLink 0000053 - Disclosure - Stock Compensation - Employee Stock Purchase Plan (Details) link:presentationLink link:calculationLink link:definitionLink 0000054 - Disclosure - Stock Compensation - Summary of Plans (Details) link:presentationLink link:calculationLink link:definitionLink 0000055 - Disclosure - Stock Compensation - Options (Details) link:presentationLink link:calculationLink link:definitionLink 0000056 - Disclosure - Stock Compensation - Valuation Assumptions (Details) link:presentationLink link:calculationLink link:definitionLink 0000057 - Disclosure - Stock Compensation - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 0000058 - Disclosure - Stock Compensation - RSUs (Details) link:presentationLink link:calculationLink link:definitionLink 0000059 - Disclosure - Stock Compensation - PBRSU's (Details) link:presentationLink link:calculationLink link:definitionLink 0000060 - Disclosure - Stock Compensation - PBSOs (Details) link:presentationLink link:calculationLink link:definitionLink 0000061 - Disclosure - Employee Benefit Plan (Details) link:presentationLink link:calculationLink link:definitionLink 0000062 - Disclosure - Leases - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 0000063 - Disclosure - Leases - Future Maturities and Supplemental Balance Sheet Information (Details) link:presentationLink link:calculationLink link:definitionLink 0000063 - Disclosure - Leases - Future Maturities and Supplemental Balance Sheet Information (Details) link:presentationLink link:calculationLink link:definitionLink 0000064 - Disclosure - Income Taxes - Summary (Details) link:presentationLink link:calculationLink link:definitionLink 0000065 - Disclosure - Income Taxes - Reconciliation (Details) link:presentationLink link:calculationLink link:definitionLink 0000066 - Disclosure - Income Taxes - Summary of Income Tax Contingencies (Details) link:presentationLink link:calculationLink link:definitionLink 0000067 - Disclosure - Income Taxes - Deferred Tax Assets (Details) link:presentationLink link:calculationLink link:definitionLink 0000068 - Disclosure - Net Loss Per Common Share - Calculation of diluted net loss per share (Details) link:presentationLink link:calculationLink link:definitionLink 0000069 - Disclosure - Statements of Cash Flows (Details) link:presentationLink link:calculationLink link:definitionLink