Recently Published Data on Bempedoic Acid


Efficacy and Safety of Bempedoic Acid Added to Maximally Tolerated Statins in Patients with Hypercholesterolemia and High Cardiovascular Risk: the CLEAR Wisdom Trial
American College of Cardiology 68th Scientific Session & Expo
Anne Carol Goldberg, MD, FACP, FAHA, FNLA

Phase 3 Evaluation of Bempedoic Acid Added to Ezetimibe in Patients with Elevated LDL-Cholesterol Receiving No Greater Than Low Dose Statins: CLEAR Tranquility
XVIIIth International Symposium on Atherosclerosis
Christie M. Ballantyne, Maciej Banach, G.B. John Mancini, Norman E. Lepor, Jeffrey C. Hanselman, Xin Zhao, Lawrence A. Leiter.

Long-term Safety, Tolerability, and Efficacy of Bempedoic Acid vs Placebo in High Cardiovascular Risk Patients with LDL-C Above 1.8 mmol/L on Maximally Tolerated Statin Therapy (CLEAR Harmony)
European Society of Cardiology (ESC) Congress
Kausik K. Ray, Harold E. Bays, Alberico L. Catapano, Narendra Lalwani, LeAnne T. Bloedon, Lulu Ren Sterling, Christie M. Ballantyne, on behalf of the CLEAR Harmony Steering Committee.


Effect of ETC-1002 on Serum Low-Density Lipoprotein Cholesterol in Hypercholesterolemic Patients Receiving Statin Therapy
American Journal of Cardiology
Christie M. Ballantyne, MD; James M. McKenney, PharmD; Diane E. MacDougall, MS; Janice R. Margulies, MS; Paula L. Robinson, MS; Jeffrey C. Hanselman, MS; and Narenda D. Lalwani, PhD, MBA.

Liver-Specific ATP-Citrate Lyase Inhibition by Bempedoic Acid Decreases LDL-C and Attenuates Atherosclerosis
Nature Communications
Stephen L. Pinkosky, Roger S. Newton, Emily A. Day, Rebecca J. Ford, Sarka Lhotak, Richard C. Austin, Carolyn M. Birch, Brennan K. Smith, Sergey Filippov, Pieter H.E. Groot, Gregory R. Steinberg, Narendra D. Lalwani.

Treatment with ETC-1002 Alone and in Combination with Ezetimibe Lowers LDL Cholesterol in Hypercholesterolemic Patients With or Without Statin Intolerance
Journal of Clinical Lipidology
Paul D. Thompson, MD; Diane E. MacDougall, MS; Roger S. Newton, PhD; Janice R . Margulies, MS; Jeffrey C. Hanselman, MS; David G. Orloff, MD; James M. McKenney, PharmD; Christie M. Ballantyne, MD.

Use of ETC-1002 to Treat Hypercholesterolemia in Patients With Statin Intolerance
Journal of Clinical Lipidology
Paul D. Thompson, MD; John Rubino, MD; Matther J. Janik, MD; Diane E. MacDougall, MS; Scott J. McBride, MA; Janice R. Margulies, MS; Roger S. Newton, PhD.