Hearts & Minds Blog

Important Bempedoic Acid-Based Franchise Progress Updates

Tim Mayleben

President and Chief Executive Officer

Last week was exciting for us at Esperion as we reported on tremendous progress achieved in enrolling patients for our bempedoic acid global pivotal Phase 3 program, as well as highly positive Phase 2 results from the combo plus statin study. The Lipid Management Team has been “heads down” making critical advancements for the bempedoic acid franchise both in the clinic and in conversations with regulators that will undoubtedly propel us to a successful second half of the year. First, as you may recall, we… more

The History of LDL-Cholesterol with Dr. Antonio Gotto | Beyond Statins: The Evolution of Cholesterol Lowering Treatments

Tim Mayleben

President and Chief Executive Officer

Antonio M. Gotto, Jr., MD, DPhil

Dean Emeritus, Weill Cornell Medicine, and Provost for Medical Affairs Emeritus, Cornell University

In Part I of our “History of LDL-cholesterol” blog series, I sat down with cardiovascular and lipids specialist, Dr. Antonio M. Gotto, Jr,. to explore the discovery of cholesterol and the development of statins. To continue our conversation focused on cholesterol-lowering treatment options, our next session was centered around therapies that have emerged after statins, and how they have changed the cholesterol treatment landscape. Dr. Gotto’s expertise and years of clinical practice always make for an informative and insightful discussion. Read on for highlights from… more

The Bempedoic Acid / Ezetimibe Combo Pill: Our Leading Complementary, Non-statin, Oral Therapy

Marianne Andreach

Senior Vice President, Strategic Marketing and Product Planning

This week we announced a major milestone: the U.S. Food and Drug Administration (FDA) confirmed the regulatory pathway to approval for an LDL-cholesterol lowering indication for our once-daily, oral combination of bempedoic acid 180 mg and ezetimibe 10 mg. The complementary, non-statin combo pill lowers LDL–cholesterol (LDL-C) by almost 50%, while significantly reducing a key marker of inflammation associated with cardiovascular disease known as high-sensitivity C-reactive protein (hsCRP), while potentially lowering the occurrence of muscle-related side effects. As you may recall, this follows our March… more

Setting the Record Straight: The Facts About Bempedoic Acid

Tim Mayleben

President and Chief Executive Officer

We recently became aware of comments published containing misinterpretations or intentionally inaccurate statements regarding Esperion and bempedoic acid.  As the press release we issued referenced, we generally do not comment on these types of communications.  However, as lipid management experts we are compelled to set the record straight about Esperion, bempedoic acid, and our fixed-dose-combination. Bempedoic Acid Clinical Development and Need for Additional Treatment Options We have conducted the most robust clinical development program for an LDL-C lowering therapy in recent memory; over 1,000 patients… more

Cardiovascular Disease Awareness: Heart Healthy Initiatives Underway at Esperion

Tricia Mullins

Executive Director, Advocacy & Professional Relations

I am very excited to join my Esperion colleagues, their families and pets to participate in the Washtenaw County American Heart Association (AHA) Heart Walk on Saturday, May 6, 2017!  Our Esperion team will be joining nearly 1 million people at 305 events across the country to build healthier lives, free of cardiovascular diseases and stroke. At Esperion we are committed to promoting awareness for healthier lives and hearts.  Esperion has challenged our team of Lipid Management Experts to the FitBit Challenge, as we explore… more